Low level of low-density lipoprotein receptor-related protein 1 predicts an unfavorable prognosis of hepatocellular carcinoma after curative resection.
BACKGROUND: Low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional receptor involved in receptor-mediated endocytosis and cell signaling.The aim of this study was to elucidate the expression and mechanism of LRP1 in hepatocellular carcinoma (HCC).METHODS: LRP1 expression in bostik roll-cote 4 HCC cell lines and 40 HCC sample